A statistics sketch · 30 September 2026

How many cases before your numbers mean anything?

When a complication is rare, a clean run feels like proof. Exact binomial arithmetic says how long that run has to be, and how often a perfectly average surgeon has a run that looks bad.

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Try some numbers

Set the baseline you compare against. Everything below updates with it. The 1% starting value is only an example, not a published rate for any operation.

A teaching sketch for building intuition, not an audit tool. A real audit needs a baseline chosen for the operation and the patients, and risk adjustment for case mix.

Observed rate
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95% interval (exact)
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Could be as high as
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Cases needed to show you’re better

Suppose your true rate is some fraction of the baseline. How many cases give you an 80% chance that the data will show it, using a one-sided exact test at the usual 5% level? Being slightly better takes enormous numbers.

Chart values
True rateCases for an 80% chance

Bad runs happen to average surgeons

Each line is a simulated surgeon whose true rate is exactly the baseline. The line is a CUSUM: it rises after each complication, drifts down after each clean case, and sounds an alarm if it crosses the threshold. The CUSUM here is set to watch for the odds of a complication doubling. Every alarm below is false.

What this does not do

Checks: the exact intervals and bounds here match SciPy’s beta-distribution values to within 10−14 on ten test cases. The case counts match an independent SciPy implementation exactly, at baselines of 1% and 5%. The CUSUM uses the standard log-likelihood-ratio weights for a Bernoulli outcome and resets to zero after an alarm.